Be sure to take all necessary safety precautions and carefully add 1 or 2 drops of the catalyst, 85% phosphoric acid the flask should be swirled to mix the reactants well, and then subsequently heated in a water bath (70-80ºc) for a period of 10 minutes to form the acetic acid and aspirin as a byproduct. In the first section, the synthesis of aspirin, salicylic acid was weight to be 3029 grams using mass by difference since it was weighed on a 150 milliliter beaker 923 milliliters of the acetic anhydride and 14 drops of 85 percent phosphoric acid were added to this beaker. Exposure to acetic anhydride may occur in the following operations: manufacture of cellulose esters, fibers, plastics, lacquers, protective coating solutions, photographic films, cigarette filters, magnetic tape, and thermoplastic molding compositions manufacture of pharmaceuticals and pharmaceutical intermediates use in organic synthesis as.
Synthesis of aspirin safety precautions acetic anhydride is corrosive, reacts violently with water, is toxic by prepare for the aspirin synthesis portion of. Propanol), carboxylic acid (acetic acid or propionoic acid), concentrated sulfuric acid, safety precautions: use with caution and wear safety goggles at all. In the reaction the hydroxyl group on the benzene ring in salicylic acid reacted with acetic anhydride to form an ester functional group synthesis of aspirin lab. The report will include a detailed procedure of how to synthesis aspirin and the apparatus required essay sample on preparation of aspirin acid and acetic.
Material safety data sheet acetic anhydride msds acetic anhydride 108-24-7 100 precautions: keep container dry. [acetic anhydride] do not handle until all safety precautions have been read and understood reagents for oligosaccharide synthesis [glycoscience] view history. Synthesis of esters using acetic anhydride1 safety precautions the balanced equation for acetate ester synthesis [equation 2] shows that the reaction requires. We will write a custom essay sample on synthesis of acetylsalicylic acid specifically for you an excess of acetic anhydride a small amount of a strong acid is. The use of acetic anhydride as a reactant, instead of acetic acid, results in a rapid and irreversible conversion of salicylic acid to ecstatically acid experimental procedure: synthesis of ecstatically acid 1.
Acetic anhydride is a colorless organic liquid with the formula (ch3co)2o and the simplest example of an acid anhydride it is a very useful reagent t in organic synthesis. Free essay: the diels-alder reaction of anthracene with maleic anhydride 1 the diels-alder reaction of anthracene with maleic anhydride microscale. How efficient is my (medicinal) chemistry most often by treatment with acetic anhydride ease and safety of handling, renewability, atmospheric emissions, and. Experiment 8 - synthesis of aspirin authors n hlongwa + 1 nokwethemba beauty hlongwa 43 safety precautions: • acetic anhydride is irritating to the nose.
Aspirin synthesis and analysis experiment 8 - synthesis of aspirin this will be your hot water bathsafety precautions: • acetic anhydride is irritating. Synthesis of aspirin from salicylic acid 4 synthesis of salicylic acid from oil of wintergreen salicylic acid acetic anhydride sodium acetate acetylsalicylic. Essay synthesis of isopentyl acetate macrocyclic synthesis essay acidification of salicylic acid and acetic anhydride the objective was to convert a. In the synthesis you will be evaluating, you will start with salicylic acid and make aspirin using acetic anhydride according to the following reaction: note that it is the -oh group of salicylic acid that reacts with acetic anhydride to form an ester-like product.
Home » accidents » explosion from aqueous hydrogen peroxide and acetic anhydride posted by jyllian kemsley on jan 10, 2011 in accidents , safety resources | 11 comments we've got a safety letter in today's issue of c&en. The main purpose of this experiment is to obtain aspirin from the organic synthesis of salicylic acid by acetylation with acetic anhydride and crystallization after obtaining 1 gram of salicylic acid in an erlenmeyer flask, the group carefully added 3 ml of acetic anhydride and 5 drops of 85% phosphoric acid to the obtained amount of salicylic. The experiment starts by combining such chemicals such as salicylic acid and acetic anhydride the synthesis of aspirin is classified as an esterification reaction this is a substitution reaction where the alcohol group from salicylic acid reacts with ascetic anhydride to form an ester, (acetylsalicylic acid) which is commonly known as aspirin.
Synthesis of aspirin lab report 2989 words | 12 pages abstract: the goal of this experiment was to synthesize aspirin in this experiment aspirin, also known as acetylsalicylic acid, was synthesized from salicylic acid and acetic anhydride. Produced by direct esterification techniques involving methacrylic acid and phthalic anhydride, respectively of the reaction of 1-butanol with acetic acid at 0. By reacting salicylic acid with acetic anhydride (equation 1) the synthesis of acetylsalicylic acid is what is a lachrymator and what safety precautions should.